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Descriptor English:   alpha-Crystallin B Chain 
Descriptor Spanish:   Cadena B de alfa-Cristalina 
Descriptor Portuguese:   Cadeia B de alfa-Cristalina 
Synonyms English:   B Chain, alpha-Crystallin
B Subunit alpha-Crystallin
Crystallins, alpha B Chain
Rosenthal Fiber Component
alpha B Crystallin
alpha B-Crystallin
alpha Crystallin B Chain
alpha Crystallin, B Subunit
alpha-Crystallin, B Subunit  
Tree Number:   D12.776.306.366.100.300
D12.776.580.157.300
Definition English:   One of the alpha crystallin subunits. In addition to being expressed in the lens (LENS, CRYSTALLINE), alpha-crystallin B chain has been found in a variety of tissues such as HEART; BRAIN; MUSCLE; and KIDNEY. Accumulation of the protein in the brain is associated with NEURODEGENERATIVE DISEASES such as CREUTZFELDT-JAKOB SYNDROME and ALEXANDER DISEASE. 
History Note English:   2003; for ALPHA B-CRYSTALLIN use CRYSTALLINS 1998-2002 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   37441 
Unique Identifier:   D038203 

Occurrence in VHL:
 

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